The Safety and Efficacy of Irreversible Electroporation for Large Hepatocellular Carcinoma
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چکیده
منابع مشابه
The Safety and Efficacy of Irreversible Electroporation for Large Hepatocellular Carcinoma
This study aimed to investigate the safety and effectiveness of irreversible electroporation ablation for unresectable large liver cancer. Fourteen patients were enrolled: 8 with large hepatocellular carcinoma (tumor diameter: 5.1-11.5 cm) and 6 with medium hepatocellular carcinoma (tumor diameter: 3.0-4.1 cm). All patients received percutaneous irreversible electroporation ablation. Ablation t...
متن کاملIrreversible electroporation of hepatocellular carcinoma: patient selection and perspectives
Irreversible electroporation (IRE) is a novel form of tissue ablation that uses high-current electrical pulses to induce pore formation of the cell lipid bilayer, leading to cell death. The safety of IRE for ablation of hepatocellular carcinoma (HCC) has been established. Outcome data for ablation of HCC by IRE are limited, but early results are encouraging and suggest equivalency to the outcom...
متن کاملIrreversible electroporation therapy in the liver: longitudinal efficacy studies in a rat model of hepatocellular carcinoma.
Irreversible electroporation (IRE) is an innovative local-regional therapy that involves delivery of intense electrical pulses to tissue to induce nanoscale cell membrane defects for tissue ablation. The purpose of this study was to investigate the feasibility of using IRE as a liver-directed ablation technique for the treatment of hepatocellular carcinoma (HCC). In the N1-S1 rodent model, hepa...
متن کاملThe optimization of needle electrode number and placement for irreversible electroporation of hepatocellular carcinoma
BACKGROUND Irreversible electroporation (IRE) is a novel ablation tool that uses brief high-voltage pulses to treat cancer. The efficacy of the therapy depends upon the distribution of the electric field, which in turn depends upon the configuration of electrodes used. METHODS We sought to optimize the electrode configuration in terms of the distance between electrodes, the depth of electrode...
متن کاملEvaluation of tolerability and efficacy of irreversible electroporation (IRE) in treatment of Child-Pugh B (7/8) hepatocellular carcinoma (HCC).
INTRODUCTION Few studies have assessed the tolerability and efficacy of irreversible electroporation (IRE) in the treatment of Child-Pugh B (7/8) patients with hepatocellular carcinoma (HCC). Based on its mechanism of action, we hypothesized that IRE would be superior to microwave (MW) ablation and compared the liver tolerance and ablation success rates of these therapies in Child-Pugh B patien...
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ژورنال
عنوان ژورنال: Technology in Cancer Research & Treatment
سال: 2016
ISSN: 1533-0346,1533-0338
DOI: 10.1177/1533034616676445